Statement $I$: In prokaryotes, the positively charged DNA is held with some negatively charged proteins in a region called nucleoid.
Statement $II$: In eukaryotes, the negatively charged DNA is wrapped around the positively charged histone octamer to form nucleosome.
In the light of the above statements, choose the correct answer from the options given below:
Reason : Trace evidences such as hairs, saliva and dried semen are adequate for $DNA$ analysis.
$(I)$ Separation of $DNA$ fragment by electrophoresis.
$(II)$ Digestion of $DNA$ by restriction endonucleases.
$(III)$ Hybridization using labeled $VNTR$ probe
$(IV)$ Isolation of $DNA$.
$(V)$ Detection of hybridized $DNA$ fragments by autoradiography.
$(VI)$ Transferring of separated $DNA$ fragment to synthetic membranes.