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MODEL PAPER 8 — BIOLOGY STD 12 Science — Question

Rajasthan BoardEnglish MediumSTD 12 ScienceBIOLOGYMODEL PAPER 83 Marks
Question
The image below eleborates enzyme-replacement therapy.
Image
i. Explain enzyme-replacement therapy to treat adenosine deaminase deficiency.
ii. Mention two disadvantages of this procedure.
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Answer

In enzyme replacement therapy, the patient is given functional ADA (Adenosine Desaminase) by injection.
Hereditary disease can be corrected by gene therapy. It is a collection of methods that allows correction or replacement of defective genes. The first gene therapy was given in 1990 to a 4 years old girl with Adenosine Deaminase (ADA) deficiency. It is caused due to the deletion of gene for adenosine deaminase.
Disadvantage
i. The patient does not completely recover from the disease.
ii. It needs periodic injections of the enzyme to the patients.

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