Question
What background information did Watson and Crick had available with them for developing a model of DNA? What was their own contribution?

Answer

Watson and Crick had the following informations which helped them to develop a model of DNA:
  1. Chargaff's Law suggesting A = T and C G.
  2. Wilkins and Franklin’s X-ray diffraction studies on DNA’s physical structure.
Based on these information, Watson and crick proposed:
  1. Complementary base-pairing of nitrogenous bases.
  2. Semi-conservative mode of replication.
  3. Occurrence of mutation through tautomerism.

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