Question
Where is the electron transport system operative in mitochondria? Explain the system highlighting the role of oxygen.

Answer

Electron Transport System (ETS): The metabolic pathway by which the electrons passes from one carrier to another is known as the electron transport system. It is operative in the inner mitochondrial membrane of mitochondria. The electrons from NADH produced in the mitochondrial matrix during the citric acid cycle are oxidised by an NADH dehydrogenase (Complex I). Electrons are then transferred to Ubiquinone that receives reducing equivalents via FADH, {generated during oxidation of succinate) by the activity of Succinic dehydrogenase (Complex II) in TCA. Reduced ubiquinone is oxidised with the transfer of electrons to cytochrome V via Cytochrome V complex (complex III). Cytochrome V acts carrier for transfer of electrons between complex III and complex IV. Complex IV refers to cytochrome c oxidase complex having cytochromes a and 3 and two copper centres.

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