(a)Hoffmann Bromanide degradation(1) The conversion of amides into amine in presence of bromine and alkali is known on Hoffmann degradation of amides.(2) An important characteristic of this reaction is that on amine with one carbon less than those in the amide is formed.(3) This reaction is an example of molecular rearrangement and involves migration of an alkyl or aryl group from the carbonyl carbon to this adjacent nitrogen atom.Example:
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