Question
Define transformation in Griffith's experiment. Discuss how it helps in the identification of DNA as the genetic material.
✓
Answer
During the course of Griffith’s experiment, bacteria changed its physical form. This was termed as transformation. In this experiment, the DNA of the S strain bacteria survived heating of bacteria. When a mice was injected with mixture of killed S strain and R strain, the mice died of pneumonia. This showed that DNA had the capability of surviving adverse circumstances and manifesting itself on return of favourable conditions. Stability and survival are key considerations for a material to be classified as genetic material. Thus, transformation in Griffith’s experiment helped in identification on DNA as genetic material.
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