| S.No | Simple distillation | Fractional distillation |
| i | By simple distillation we can separate two miscible liquide having sufficient difference in their boilding points | By fractional distillation, we can separate a mixture of two or more miscible liquide for which the difference in the boiling points is less than $25^\circ\ C$. |
| ii | It is done by using an air condenser or a water condenser. | A fractionating column is fitted in between the distillation flask and the condenser for the process. |