Question
What are the different types in which genes could be delivered during gene therapy?

Answer

Genes can be delivered by three ways:
  1. Ex vivo delivery : In this type of gene delivery, viral or non-viral vectors are used to introduce the desired gene in the cells isolated from patient, e.g. Parkinson’s disease, a neurological disorder.
  2. In vivo delivery : In this method, therapeutic genes are directly delivered at the target sites of the cells of diseased tissue. Intravenous infusion genes are injected directly into tumor in the treatment of cancer.
  3. Use of virosomes (Liposome + inactivated HIV), bionic chips.

Need a full question paper?

Generate a complete, print-ready paper with questions like this in minutes — across 16+ boards, with answer keys.

Start Generating Free

Similar questions

Write any four ways used to introduce a desired DNA segment into a bacterial cell in recombinant DNA technology experiments.
Suggest the reproduction-related aspects in which counselling should be provided at the school level.
Given below is a list of six micro-organisms. State their usefulness to humans.
  1. Nucleopolyhedrovirus.
  2. Saccharomyces cerevisiae.
  3. Monascus purpureus.
  4. Trichoderma polysporum.
  5. Penicillium notatum.
  6. Propionibacterium sharmanii.
Describe the termination process of transcription in bacterium.
A doctor prescribed morphine as a sedative and pain killer to your cousin who had undergone surgery. Even after recovery, he craved for the prescribed medicine. What do you conclude about his condition, had he continued with the same medication? After appraising yourself, what measures will you suggest to him to overcome this problem? Briefly explain any two.
What is a recombinant DNA vaccine? Give two examples.
  1. Name the selectable markers in the cloning vector pBR322? Mention the role they play.
  2. Why is the coding sequence of an enzyme (â-galactosidase) a preferred selectable marker in comparison to the ones named above?
Study the given pedigree chart and answer the questions that follow:
  1. Is the trait recessive or dominant?
  2. Is the trait sex-linked or autosomal?
  3. Give the genotypes of the parents shown in generation I and their third child shown in generation II and the first grandchild shown in generation III.
  1. Name the infective stage Plasmodium which Anopheles mosquito takes in along with the blood meal from an infected human.
  2. Why does the infection cause fever in human?
  3. Give a flow chart of the part of the life-cycle of this parasite passed in the insect.
Answer the following questions:
Still it is observed that it does not form a continuous layer around the pollen grain. Give reason.