Question
What is the relation between immunity and organ transplantation?
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Answer
- Those who undergo an organ transplant face the possibility that their immune system will reject their new organ and that they will always be at a higher risk for infections.
- The immune system is able to recognize the difference between cells that belong to our body and those that do not by learning to identity protein markers (antigens) that are found on cell and infection surfaces.
- In people, the antigens or markers that identity their immune system are referred to as the human leukocyte antigen (HLA).
- Antigens that are recognized as unfriendly invaders stimulate an immune response to destroy them.
- Therefore, when organ transplantation is done, the immune responses are temporarily stalled. This helps in acceptance of the graft in the recipient’s body.
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