Why is it necessary to avoid even traces of moisture during the use of a Grignard reagent?
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Grignard reagents are highly reactive and react with any source of proton to yield hydrocarbons. Even water, alcohols and amines are sufficiently acidic to convert them to corresponding hydrocarbons.
It is therefore necessary to avoid even traces of moisture from a Grignard reagent.
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Arrange the compounds of each set in order of reactivity towards $S_N2$ displacement: $1-$Bromobutane, $1-$Bromo$-2,2-$dimethylpropane, $1-$Bromo$-2-$methylbutane, $1-$Bromo$-3-$methylbutane.
Name the following halides according to $\text{IUPAC}$ system and classify them as alkyl, allyl, benzyl $($primary, secondary, tertiary$),$ vinyl or aryl halides: $\ce{m-ClCH_2C_6H_4CH_2C(CH_3)_3}$
Write the structure of the major organic product in each of the following reaction:
$\text{CH}_3\text{CH}_2\text{CH}_2\text{OH}+\text{SOCl}_2\xrightarrow{}$
Predict all the alkenes that would be formed by dehydrohalogenation of the following halides with sodium ethoxide in ethanol and identify the major alkene:
2,2,3-Trimethyl-3-bromopentane.
Write the structure of the major organic product in each of the following reaction:
$\text{CH}_3\text{CH}_2\text{Br}+\text{KCN}\xrightarrow{\text{aq. ethanol}}$