Question
With the help of a suitable example illustrate Palindrome.
✓
Answer
A palindromic sequence is a sequence made up of nucleic acids within double helix of DNA and/or RNA that is the same when read from 5’ to 3’ on one strand and 5’ to 3’ on the other, complementary, strand. It is also known as a palindrome or an inverted-reverse sequence.
The pairing of nucleotides within the DNA double-helix is complementary which consist of Adenine (A) pairing with either Thymine (T) in DNA or Uracil (U) in RNA, while Cytosine (C) pairs with Guanine (G). So if a sequence is palindromic, the nucleotide sequence of one strand would be the same as its reverse complementary strand. An example of a palindromic sequence is 5’-GGATCC-3’, which has a complementary strand, 3’-CCTAGG-5’. This is the sequence where the restriction endonuclease, BamHI, binds to and cleaves at a specific cleavage site. When the complementary strand is read backwards, the sequence is 5’-GGATCC-3’ which is identical to the first one, making it a palindromic sequence.
Another restriction enzyme called EcoR1 recognizes and cleaves the following palindromic sequence:
$(5^{\prime}- GAATTC -3^{\prime}$
$3^{\prime}- CTTAAG -5^{\prime})$
The pairing of nucleotides within the DNA double-helix is complementary which consist of Adenine (A) pairing with either Thymine (T) in DNA or Uracil (U) in RNA, while Cytosine (C) pairs with Guanine (G). So if a sequence is palindromic, the nucleotide sequence of one strand would be the same as its reverse complementary strand. An example of a palindromic sequence is 5’-GGATCC-3’, which has a complementary strand, 3’-CCTAGG-5’. This is the sequence where the restriction endonuclease, BamHI, binds to and cleaves at a specific cleavage site. When the complementary strand is read backwards, the sequence is 5’-GGATCC-3’ which is identical to the first one, making it a palindromic sequence.
Another restriction enzyme called EcoR1 recognizes and cleaves the following palindromic sequence:
$(5^{\prime}- GAATTC -3^{\prime}$
$3^{\prime}- CTTAAG -5^{\prime})$
Need a full question paper?
Generate a complete, print-ready paper with questions like this in minutes — across 16+ boards, with answer keys.
Explore more
Similar questions
Given below is the representation of amino acid composition of the relevant translated portion of b–chain of haemoglobin, related to the shape of human red blood cells.
Is this representation indicating a normal human or a sufferer from certain related genetic disease? Give reason in support of your answer.
Is this representation indicating a normal human or a sufferer from certain related genetic disease? Give reason in support of your answer.
In the given diagram, write the names of parts shown with lines.
What are vegetative propagules? Name any four of them along with an example for each.
Explain the changes that milk undergoes when suitable starter/ inoculum is added to it. How does the end product formed prove to be beneficial for human health?
Explain natural selection with example of industrial melanism
Give scientific : Cerebellum is well developed in humans.
Describe the termination process of transcription in bacterium.
Baculoviruses are good examples of biocontrol agents. Justify giving three reasons.
A woman has certain queries as listed below, before starting with contraceptives pills. Answer them.
- What do contraceptive pills contain and how do they act as contraceptives?
- What schedule should be followed for taking these pills?
What is the natural ageing of a lake called? How is it caused? Write the impact of uncontrolled human activities on it?