With the help of suitable diagrams, explain the five stages of prophase-I of meiosis.
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Prophase-I: Prophase – I of meiosis is much longer phase of the meiosis.
It is subdivided into 5 substages, namely leptotene, zygotene, pachytene, diplotene, and diakinesis.
(1) Leptotene: Initially the chromosomes start condensation and they become compact during leptotene.

(2) Zygotene: In zygotene, homologous chromosomes start pairing. This pairing is called synapsis. The structure called synaptonemal complex develops to hold chromosomes in place during this pairing. Each chromosome’s chromatid arm divides and forms structure called bivalent or tetrad.

(3) Pachytene: During pachytene stage, crossing over of non-sister chromatids of homologous chromosomes takes place. Genetic recombination is produced due to such exchange. The homologous chromosomes still remain paired together at the sites of crossing over.

(4) Diplotene: During diplotene, synaptonemal complex dissolves and the homologous chromosomes of the bivalents separate except at the point of crossing over. Thus, it looks like X-shaped structures called the chiasmata.

(5) Diakinesis: The last phase of prophase is for termination of chiasmata. The spindle fibres originate, and the cross-over homologous chromosomes are now separated. The nucleQlus disappears, and the nuclear envelope breaks down.

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